| dc.description.abstract | <p><strong>Background</strong></p>
<p>The prevalence of primary ovarian insufficiency (POI) is very variable, but it has been estimated to be around 1% of the general population in studies. It's also very likely that the prevalence of POI varies over time and between countries. It is critical to research the prevalence of premature ovarian failure in a certain context and population group in order to give thorough medical information and surveillance.</p>
<p>Therefore, the purpose of this study is to review primary premature ovarian insufficiency among women seeking infertility care at St. Paul’s Hospital Millennium Medical College, Michu reproductive health care Addis Ababa, Ethiopia.<br><br><strong>Objective: </strong>the objective of the study is to review primary premature ovarian insufficiency among women seeking infertility care at St. Paul’s Hospital Millennium Medical College, Michu reproductive health care Addis Ababa, Ethiopia.</p>
<p><strong>Methods</strong></p>
<p>A hospital based cross sectional study was conducted at SPHMMC Michu reproductive health care, Addis Ababa from January 1 /2021 – June 30 /2021. No sample size determination all women who were diagnosed with primary POI during the study period was studied. Data was collected by trained data collectors using a structured questionnaire. Data from questioner were checked and cleaned for completeness and consistency. Data were then analyzed using Statistical Package for the Social Science (SPSS) Version 23 statistical software.</p>
<p><strong>Results</strong></p>
<p>Out of 1360 women, 180 (13.2%) women had premature ovarian insufficiency. Among all women with POI, 174 (96.6%) had spontaneous POI and 6 (3.3%) had iatrogenic POI corresponding to a prevalence of 12.8% of spontaneous POI and 0.4% of iatrogenic POI. 2/3<sup>rd</sup> of the study participants was between the ages of 35 - 39, accounting for 65.5 percent of the total. In this study, there were 17 women (9.8%) who had a first-degree relative with early ovarian insufficiency. Five of the total study participants have a history of tuberculosis, all of whom received anti-tb treatment. From the study participant 88 women had short term impact of Premature ovarian insufficiency which is 50.5 percent which is a very significant number Despite the hypoestrogenic effect, none of the study participants are on hormonal replacement medication.</p>
<p><strong>Conclusion</strong></p>
<p>In conclusion, POI is prevalent, apparently more prevalent than often previously reported. The study's participants were mostly between the ages of 35 and 39. The majority of the patents in this study are nulliparous, and half of them had a history of irregular menstrual cycles before being diagnosed with Premature ovarian insufficiency. 1/4<sup>th</sup> of patients with premature ovarian failure had a history of early menopause in their family</p> | en_US |
