| dc.description.abstract | <p><strong>Introduction</strong><strong>: </strong>meconium stained amniotic fluid occurs in 12 to 20% of laboring mothers and it is a confusing issue because it can be due to either physiologic or a hypoxic insult to the fetus.</p>
<p><strong>Objective</strong>: the objective of the study was to determine perinatal outcome of laboring mothers with MSAF compared with clear amniotic fluid at SPHMMC.</p>
<p><strong>Methods</strong>: facility based prospective cohort study was conducted among laboring mothers with MSAF at SPHMMC from July 1 to December 30, 2017. Data was collected with pretested structured questionnaires and entered and analyzed using SPSS version 23. Chi-square test was used to check statistical associations between variables and 95% CI and p value set at 0.05 was used to determine the significance of the association. Cross tabulation was done and RR used to determine the strength and direction of association.</p>
<p><strong>Result</strong><strong>: </strong>among 438 participants, Primigravidas accounted for a majority<strong> </strong>of participants. 91 (63%) exposed group had gestational ages of more than 40 weeks. Labour induced in25 (17.4%) of exposed group compared to 25(8.6 %) of none exposed group and induced labour has statistically significant association with meconium staining of amniotic fluid. Caesarean section rates were nearly double in exposed group 62 (44 %). Neonatal outcome was poor in terms of low Apgar score at birth, birth asphyxia; neonatal sepsis, MAS, neonatal death and increased neonatal admission among exposed group as compared to none exposed ones.</p>
<p><strong>Conclusion and recommendations:</strong><strong> </strong>meconium stained amniotic fluid is really worrisome as it increases the caesarean rates, causes birth asphyxia, neonatal sepsis, MAS and increases neonatal intensive care unit admissions. Therefore, management requires, appropriate intrapartum care and a combined obstetric-neonatal approach in cases with MSAF.</p> | en_US |
